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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TNNI3K
All Species:
9.7
Human Site:
S716
Identified Species:
21.33
UniProt:
Q59H18
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q59H18
NP_001106279.1
936
104179
S716
G
E
S
R
F
L
Q
S
L
D
E
D
N
M
T
Chimpanzee
Pan troglodytes
XP_513493
949
105567
S729
G
E
S
R
F
L
Q
S
L
D
E
D
N
M
T
Rhesus Macaque
Macaca mulatta
XP_001097254
949
105560
S729
G
E
S
R
F
L
Q
S
L
D
E
D
N
M
T
Dog
Lupus familis
XP_537112
1087
119299
A874
E
D
G
H
A
V
V
A
D
F
G
E
S
R
F
Cat
Felis silvestris
Mouse
Mus musculus
Q5GIG6
834
92569
Q623
D
E
D
N
M
T
K
Q
P
G
N
L
R
W
M
Rat
Rattus norvegicus
Q7TQP6
835
92713
Q624
D
E
D
N
M
T
K
Q
P
G
N
L
R
W
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001339957
835
92821
Q624
D
E
D
N
M
T
K
Q
P
G
N
L
R
W
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_001021182
850
93167
K639
Y
L
H
E
S
A
A
K
P
V
I
H
R
D
L
Sea Urchin
Strong. purpuratus
XP_782227
862
95496
N651
V
K
S
M
H
E
D
N
M
T
K
Q
P
G
N
Poplar Tree
Populus trichocarpa
XP_002336079
539
60951
F328
R
H
K
N
V
V
K
F
I
G
A
C
T
R
P
Maize
Zea mays
NP_001152032
543
61643
Y332
H
E
N
I
L
Q
F
Y
G
A
C
T
K
H
P
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.2
96.5
80.1
N.A.
80.7
81.3
N.A.
N.A.
N.A.
N.A.
75.7
N.A.
N.A.
N.A.
36.7
51.1
Protein Similarity:
100
98.3
97.2
82.6
N.A.
84.4
85.3
N.A.
N.A.
N.A.
N.A.
83.7
N.A.
N.A.
N.A.
55
65.6
P-Site Identity:
100
100
100
0
N.A.
6.6
6.6
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
N.A.
0
6.6
P-Site Similarity:
100
100
100
33.3
N.A.
13.3
13.3
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
N.A.
0
33.3
Percent
Protein Identity:
23.6
22.4
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
37.2
36.2
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
0
6.6
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
20
13.3
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
10
10
10
0
10
10
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
10
10
0
0
0
% C
% Asp:
28
10
28
0
0
0
10
0
10
28
0
28
0
10
0
% D
% Glu:
10
64
0
10
0
10
0
0
0
0
28
10
0
0
0
% E
% Phe:
0
0
0
0
28
0
10
10
0
10
0
0
0
0
10
% F
% Gly:
28
0
10
0
0
0
0
0
10
37
10
0
0
10
0
% G
% His:
10
10
10
10
10
0
0
0
0
0
0
10
0
10
0
% H
% Ile:
0
0
0
10
0
0
0
0
10
0
10
0
0
0
0
% I
% Lys:
0
10
10
0
0
0
37
10
0
0
10
0
10
0
0
% K
% Leu:
0
10
0
0
10
28
0
0
28
0
0
28
0
0
10
% L
% Met:
0
0
0
10
28
0
0
0
10
0
0
0
0
28
28
% M
% Asn:
0
0
10
37
0
0
0
10
0
0
28
0
28
0
10
% N
% Pro:
0
0
0
0
0
0
0
0
37
0
0
0
10
0
19
% P
% Gln:
0
0
0
0
0
10
28
28
0
0
0
10
0
0
0
% Q
% Arg:
10
0
0
28
0
0
0
0
0
0
0
0
37
19
0
% R
% Ser:
0
0
37
0
10
0
0
28
0
0
0
0
10
0
0
% S
% Thr:
0
0
0
0
0
28
0
0
0
10
0
10
10
0
28
% T
% Val:
10
0
0
0
10
19
10
0
0
10
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
28
0
% W
% Tyr:
10
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _